Human genes with relative synonymous codon usage analogous to that of polyomaviruses are involved in the mechanism of polyomavirus nephropathy
Human polyomaviruses (HPyVs) can cause serious and deleterious infections in human.Yet, the molecular mechanism underlying these infections, particularly in polyomavirus nephropathy (PVAN), is not well-defined.In the present study, we aimed to identify human genes with codon usage bias (CUB) similar to that of HPyV genes and explore their potential